Autophagy supports genomic stability by degrading retrotransposon RNA

Huishan Guo, Maneka Chitiprolu, David Gagnon, Lingrui Meng, Carol Perez-Iratxeta, Diane Lagace, and Derrick Gibbings. Nature Communications, 5: 5276, 2014.

Tissue-specific gene silencing monitored in circulating RNA.

Alfica Sehgal, Qingmin Chen, Derrick Gibbings, Dinah Sah, and David Bumcrot. RNA, 20:143-149, 2014.

Autophagy selectively regulates miRNA homeostasis.

Derrick Gibbings, Serge Mostowy and Olivier Voinnet. Autophagy selectively regulates miRNA homeostasis. Autophagy, 5: 781-783, 2013.

Selective autophagy degrades DICER and AGO2 and regulates miRNA activity.

Derrick Gibbings, Serge Mostowy, Florence Jay, Yannick Schwab, Pascale Cossart and Olivier Voinnet.Selective autophagy degrades DICER and AGO2 and regulates miRNA activity. Nature Cell Biology. 14: 1314-1321, 2012.

The Prion Protein Binds Argonaute and Promotes Accumulation of MicroRNA Effector Complexes.

Derrick Gibbings, Pascal Leblanc, Florence Jay, Dominique Pontier, Yannick Schwab, Fabrice Michel, Sandra Alais, Thierry LaGrange, and Olivier Voinnet. The Prion Protein Binds Argonaute and Promotes Accumulation of MicroRNA Effector Complexes. Nature Structural and Molecular Biology, 19: 517-524, 2012.

Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels

Yamina Bennasser, Christine Chable-Bessia, Robinson Triboulet, Derrick Gibbings, Carole Gwizdek, Catherine Dargemont, Eric J Kremer, Olivier Voinnet and Monsef Benkirane. Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels. Nature Structural & Molecular Biology. 18: 323–327, 2011.

Continuous Density Gradients to Study Argonaute and GW182 Complexes Associated with the Endocytic Pathway

Derrick Gibbings. Continuous Density Gradients to Study Argonaute and GW182 Complexes Associated with the Endocytic Pathway. Methods Mol Biol. 725:63-76, 2011.

Regulation of RNA Localization and Silencing by the Endolysosomal System.

Derrick Gibbings and Olivier Voinnet. Regulation of RNA Localization and Silencing by the Endolysosomal System. Trends in Cell Biology, 20: 491-501, 2010.

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity.

Derrick Gibbings, Constance Ciaudo, Mathieu Erhardt and Olivier Voinnet. Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nature Cell Biology, 11: 1143-1149, 2009.